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CHICAGO–(BUSINESS WIRE)–Feb. 23, 2006–Allscripts (Nasdaq:MDRX),
the leading provider of clinical software, connectivity and
information solutions that physicians use to improve healthcare, today
announced that its Physicians Interactive(TM) Group has been selected
by Shire Pharmaceuticals, a leading global specialty pharmaceutical
company, to design, deploy and support a strategic eMarketing solution
for Shire’s US business.

The Agreement calls for Physicians Interactive to deliver its
turn-key Enterprise eMarketing Solution to be leveraged for Shire’s
online marketing programs to US physicians. The Enterprise eMarketing
Solution can support a full suite of online management tools,
including product updates, physician communication and education,
sample and rep requests, as well as eDetailing(TM) opportunities. All
of these eMarketing services are driven through a sophisticated
“physician-centric” relational database.

The Enterprise eMarketing Solution increases Shire’s value to
physicians by providing convenient access to strategic product
education and resources online. This solution is driven by physician
preferences and dynamically deploys the right information and
education at the right time. Services are available to physicians 24
hours a day, seven days a week, and providing Shire real-time
reporting to continually learn the needs of the physicians they serve
on a day-to-day basis.

“At Shire, our mission is to be the best at meeting the needs of
specialty physicians,” stated Bob Harrell, Director of eMarketing for
Shire. “The Enterprise e-Marketing Solution from Allscripts allows us
to provide clinical information and education to our specialty
audiences online, complementing our direct field force and other
non-personal promotion efforts. The rich functionality of this
platform gives us a powerful means to deploy programs for physicians
across various Shire products.”

Allscripts can deploy the Enterprise e-Marketing platform through
a hosted ASP-model or through a software license. A team of system
developers, database experts, and implementation personnel provides a
turn-key set of services to bring the platform live in as little as 90

“We are very pleased to be partnering with Shire, a market leader
in specialty pharmaceuticals,” stated Mark Thierer, President of
Allscripts Physicians Interactive Group. “With the deployment of
Allscripts’ Enterprise e-Marketing Solution, Shire is extending its
leadership position by acquiring a platform that allows them to build
an “Electronic Dialogue” with physicians.”

About Shire

Shire’s strategic goal is to become the leading specialty
pharmaceutical company that focuses on meeting the needs of the
specialist physician. Shire focuses its business on central nervous
system (CNS), gastrointestinal (GI), general products (GP) and human
genetic therapies (HGT) – all being areas in which Shire has a
commercial presence. The structure is sufficiently flexible to allow
Shire to target new therapeutic areas to the extent opportunities
arise through acquisitions. Shire believes that a carefully selected
portfolio of products with a strategically aligned and relatively
small-scale sales force will deliver strong results. Shire’s focused
strategy is to develop and market products for specialty physicians.
This approach aims to deliver increased returns and lower risks.
Shire’s in-licensing and merger and acquisition efforts are focused on
products in niche markets with strong intellectual property protection
either in the US or Europe. For further information on Shire, please
visit the Company’s website:

About Allscripts

Allscripts is the leading provider of clinical software,
connectivity and information solutions that physicians use to improve
healthcare. The Company’s business groups provide unique solutions
that inform, connect and transform healthcare. The Clinical Solutions
Group’s award-winning clinical software applications include
Electronic Health Record, e-prescribing and document imaging
solutions. Additionally, Allscripts provides clinical product
education and connectivity solutions for physicians and patients
through its Physicians Interactive(TM) Group and medical fulfillment
services through its Medication Services Group. To learn more, visit
Allscripts on the Web at

This announcement may contain forward-looking statements about
Allscripts that involve risks and uncertainties. These statements are
developed by combining currently available information with Allscripts
beliefs and assumptions. Forward-looking statements do not guarantee
future performance. Because Allscripts cannot predict all of the risks
and uncertainties that may affect it, or control the ones it does
predict, Allscripts’ actual results may be materially different from
the results expressed in its forward-looking statements. For a more
complete discussion of the risks, uncertainties and assumptions that
may affect Allscripts, see the Company’s 2004 Annual Report on Form
10-K, available through the Web site maintained by the Securities and
Exchange Commission at

    CONTACT: Allscripts Physicians Interactive Contact:
             Rita Glaze, 800-654-0889 Ext. 4806

    SOURCE: Allscripts
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