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Sale of Leading Online Physician Education Solution to Perseus, L.L.C. Enables
               Both Companies to Focus on Their Core Businesses

CHICAGO and WASHINGTON, Sept. 19 /PRNewswire-FirstCall/ — Allscripts
Healthcare Solutions, Inc., the leading provider of clinical software,
connectivity and information solutions that physicians use to improve
healthcare, announced today it has signed a definitive agreement to sell its
Physicians Interactive(R) business unit to a fund managed by Perseus, L.L.C.,
a merchant bank and private equity fund management company.

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The transaction is scheduled to close on or about October 3, 2008, subject
to customary closing conditions.

Physicians Interactive develops online clinical education programs that
enable life sciences companies to reach physicians. The company’s free, online
solutions for healthcare providers deliver timely clinical information and
educational programs while building an electronic dialogue between physicians
and life sciences companies.

The acquisition by Perseus Acquisitions Holdings LLC will allow Physicians
Interactive to continue to grow its business and more aggressively invest in
new opportunities that expand and build upon its current product portfolio.
The transaction will allow Allscripts to focus on its core business of
providing information and connectivity solutions to physicians and hospitals,
which continues to grow. The pending merger of Allscripts with Misys
Healthcare would create a new company with a client base of nearly one-third
of the practicing physicians in America.

“This is a win-win for Allscripts and Physicians Interactive,” said Glen
Tullman, Chief Executive Officer of Allscripts. “The sale of Physicians
Interactive is an important step that will enable Allscripts to concentrate
our resources on achieving our goals, while providing Physicians Interactive
the right opportunity to continue to develop its set of solutions.”

“We are very excited to acquire Physicians Interactive,” said Norman
Selby, Senior Managing Director of Perseus, LLC. “We plan to build on the
strengths that Physicians Interactive already has and invest aggressively to
increase the value it provides to physicians, nurses and other healthcare
providers, and the pharmaceutical, biotech and medical device companies that
want to reach them. Our goal is to create a company that has the leading suite
of alternative channel marketing and sales products and programs to serve
pharmaceutical, biotech and device customers, including direct mail,
eDetailing, video detailing, eCME, market research, surveys, eSampling,
eNewsletters, blogs and social networking.”

As part of the transaction, Allscripts President Lee Shapiro will assume a
seat on the board of directors of Perseus Acquisitions Holdings LLC.

Additionally, Allscripts and Perseus/Physicians Interactive have signed an
agreement to explore innovative and unique offerings that leverage Allscripts
strengths as the leading provider of Electronic Health Records and
ePrescribing solutions for physicians, and Physicians Interactive’s strengths
in communicating with and educating providers.

About Perseus

Perseus, L.L.C. is a merchant bank and private equity fund management
company with offices in Washington, D.C., New York and Munich. Since its
inception in 1995, Perseus has invested in numerous buyout and growth equity
transactions in the United States, Canada, and Western Europe. Perseus manages
seven investment funds with capital commitments totaling approximately $2.0

About Physicians Interactive

Physicians Interactive builds an electronic dialogue with healthcare
professionals by utilizing technology platforms and online interactive
programs to deliver valuable education and promotion about medical products
and disease states. Since 1996, Physicians Interactive has developed over 950
online programs for more than 150 brands throughout every stage of the product
life cycle. Physicians Interactive’s client list includes nearly 75
pharmaceutical, biotech, and medical device companies, including nine of the
top 10 worldwide pharmaceutical corporations. For more information, visit

About Allscripts

Allscripts (Nasdaq: MDRX) is the leading provider of clinical software,
connectivity and information solutions that physicians use to improve
healthcare. The company’s unique solutions inform, connect and transform
healthcare, delivering improved care at lower cost. More than 40,000
physicians and thousands of other healthcare professionals in clinics,
hospitals and extended care facilities nationwide utilize Allscripts to
automate everyday tasks such as writing prescriptions, documenting patient
care, managing billing and scheduling, and safely discharging patients, as
well as to connect with key information and stakeholders in the healthcare
system. To learn more, visit Allscripts at

This announcement may contain forward-looking statements about Allscripts
Healthcare Solutions that involve risks and uncertainties. These statements
are developed by combining currently available information with Allscripts
beliefs and assumptions. Forward-looking statements do not guarantee future
performance. Because Allscripts cannot predict all of the risks and
uncertainties that may affect it, or control the ones it does predict,
Allscripts’ actual results may be materially different from the results
expressed in its forward-looking statements. For a more complete discussion of
the risks, uncertainties and assumptions that may affect Allscripts, see the
Company’s 2007 Annual Report on Form 10-K, available through the Web site
maintained by the Securities and Exchange Commission at

SOURCE  Allscripts Healthcare Solutions, Inc.
    -0-                             09/19/2008
    /CONTACT:  Dan Michelson, Chief Marketing Officer, +1-312-506-1217, or, or Todd Stein, Senior Manager-Public Relations,
+1-312-506-1216, or, both for Allscripts; Nancy
Kavadas, Director of Marketing of Perseus-Physicians Interactive,
+1-312-961-2018, or
             AP Archive:
           PRN Photo Desk, /
    /Web site:

CO:  Allscripts Healthcare Solutions, Inc.; Physicians Interactive; Perseus
     Acquisitions Holdings LLC; Perseus, L.L.C.; Misys Healthcare
ST:  Illinois, District of Columbia

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2343 09/19/2008 14:12 EDT
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