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CHICAGO, Nov. 11, 2010 /PRNewswire via COMTEX/ —

Allscripts Healthcare Solutions, Inc. (Nasdaq: MDRX) today announced that it has commenced an underwritten public offering of 12,500,000 shares of its common stock on behalf of certain wholly owned subsidiaries of Misys plc. Allscripts will not sell any shares in the offering and will not receive any proceeds from the offering.

Barclays Capital, Inc. will act as sole book-running manager of the offering.

A shelf registration statement relating to the offering of the common shares has been filed with the U.S. Securities and Exchange Commission and has become effective. The offer is being made by the selling stockholders only by means of a prospectus supplement and accompanying prospectus. Before investing, you should read the prospectus supplement and the accompanying prospectus (including the documents incorporated by reference therein) for information about Allscripts, the selling stockholders and this offering.

This press release shall not constitute an offer to sell or the solicitation of any offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. A copy of the prospectus supplement and the accompanying prospectus relating to the offering may be obtained by contacting: Barclays Capital, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, (888) 603-5847.

About Allscripts

Allscripts (NASDAQ: MDRX) provides innovative solutions thatempower all stakeholders across the healthcare continuum todeliver world-class outcomes. The company’s clinical, financial, connectivity and information solutions for hospitals, physicians and post-acute organizations are the essential technologies that enable a connected healthcare community.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the federal securities laws. Statements regarding future events or developments, our future performance, as well as management’s expectations, beliefs, intentions, plans, estimates or projections relating to the future are forward-looking statements with the meaning of these laws. These forward-looking statements are subject to a number of risks and uncertainties. Actual results and future events could differ materially from those anticipated in such forward-looking statements.As a result, no assurances can be given that any of the events anticipated by the forward-looking statements will transpire or occur, or if any of them do so, what impact they will have on our results of operations or financial condition. See our Annual Report on Form 10-K for the fiscal year ended May 31, 2010 and other public filings with the SEC for a further discussion of risks and uncertainties applicable to our business. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of their date. We undertake no duty to update any forward-looking statement whether as a result of new information, future events or changes in expectations.

SOURCE Allscripts Healthcare Solutions, Inc.

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